When ambitious young real estate agent Leigh is asked to sell a house with a checkered past, she crosses paths with a disturbed girl whom she learns is the runaway daughter of the couple selling the property. When Leigh tries to intervene and help her, she becomes entangled with a supernatural force that soon pulls Leigh's artist sister Vera into its web - and has sinister plans for both of them.

K-11 follows Raymond Saxx Jr. (Goran Visnjic), a powerful record producer who wakes from a drug-induced blackout to find himself locked up and classified "K-11." Plunged into a nightmarish world ruled by a transsexual diva named Mousey (Kate del Castillo), Raymond is truly a fish out of water. Complicating matters are a troubled young transgender named Butterfly (Portia Doubleday), a predatory child molester (Tommy 'Tiny' Lister) and the ruthless Sheriff's Deputy, Lt. Johnson (D.B. Sweeney). Ray's struggle to contact the outside world and regain his freedom seems impossible, but he must learn to navigate this new power structure if he is ever going survive and be in control of his life again.

Charlie Rankin, recently released from prison, seeks vengeance for his jail-house mentor William "The Buddha" Pettigrew. Along the way, he meets the ethereal, yet streetwise, Florence Jane. They embark on a unlikely road trip, careening towards an unlikely redemption and uncertain resolution.